STAT6 Antibody

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Immunohistochemistry-Paraffin: STAT6 Antibody [NBP1-36531] - Human Placenta

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-36531
    • Availability
      Product Discontinued

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STAT6 Antibody Summary

Immunogen
A synthetic peptide derived from C-terminus of human STAT6
Localization
Cytoplasm, nucleus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STAT6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Human. Predicted cross-reactivity based on sequence identity: Mouse, Dog, Hamster, Pig, Rabbit.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.6) and 1.0% BSA
Preservative
0.099% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for STAT6 Antibody

  • D12S1644
  • EC 2.4.1.227
  • EC 2.7.7.6
  • IL-4 Stat
  • IL-4-STAT
  • signal transducer and activator of transcription 6
  • signal transducer and activator of transcription 6, interleukin-4 induced
  • STAT, interleukin4-induced
  • STAT6
  • STAT6B
  • STAT6C
  • transcription factor IL-4 STAT

Background

Janus family tyrosine kinases (Jaks) and signal transducers and activators of transcription (STATs) are involved in mediating gene expression in response to cytokines and interferons. Jaks associate with cytokine receptors; upon ligand binding, Jaks phosphorylate the receptor. The phosphorylated receptors are bound by SH2-containing proteins, one class of which is the STATs. Activated STATs, then, translocate to the nucleus to mediate gene transcription (1,2). Stat-6 is tyrosine phosphorylated in response to cellular interaction with IL-3 and IL-4 (3,4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional STAT6 Products

Bioinformatics Tool for STAT6 Antibody (NBP1-36531)

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Diseases for STAT6 Antibody (NBP1-36531)

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Bioinformatics

Gene Symbol STAT6
Entrez
Uniprot