STAT3 Antibody


Western Blot: STAT3 Antibody [NB100-91972] - Western blot (WB) analysis of STAT3 (P699) antibody in extracts from K562 cells.
Immunohistochemistry: STAT3 Antibody [NB100-91972] - Immunohistochemistry (IHC) analyzes of STAT3 (P699) antibody in paraffin-embedded human breast carcinoma tissue.

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
1.0 mg/ml

Order Details

STAT3 Antibody Summary

Synthetic peptide, corresponding to amino acids 680-720 of Human Stat3.
STAT3 (P699) detects endogenous levels of STAT3 (P699) protein.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Phosphate buffered saline, pH 7.2.
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


Application Notes
Western blot (WB) analysis of STAT3 (P699) pAb in extracts from K562 cells.
Immunohistochemistry (IHC) analyzes of STAT3 (P699) pAb in paraffin-embedded human breast carcinoma tissue.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
88 kDa

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat.

Alternate Names for STAT3 Antibody

  • Acute-phase response factor
  • APRFMGC16063
  • DNA-binding protein APRF
  • FLJ20882
  • HIES
  • signal transducer and activator of transcription 3 (acute-phase responsefactor)
  • signal transducer and activator of transcription 3


Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-alpha and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3beta appears to be activated by both while Stat3alpha is activated by EGF, but not by IL-6. Highest expresion of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Survivin Acetylation: Affecting Apoptosis and Cancer
Survivin (BRIC5) is an inhibitor of apoptosis that also promotes cellular adaptation under stressful conditions and helps to regulate cell division. Recently, an antibody study by Dr. H Wang et al. at Brown University [PMID: 20826784] found that Survi...  Read full blog post.

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Product PDFs


Gene Symbol STAT3

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