STAT2 Antibody (1021D) [Alexa Fluor® 488] (IC8627G)

Images

 
Daudi human Burkitt's lymphoma cell line untreated (open histogram) or treated with 500 U/mL Recombinant Human IFN‑ alpha A (Catalog # 11100-1) for 20 minutes was stained with Rabbit Anti-Human STAT2 Alexa Fluor® ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICFlow
Clone
1021D
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 488

STAT2 Antibody (1021D) [Alexa Fluor® 488] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Phosphopeptide containing the human STAT2 Y689 site
Specificity
Detects human phospho-STAT2 (Y689) in Western blots.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
STAT2
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 5 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for STAT2 Antibody (1021D) [Alexa Fluor® 488]

  • interferon alpha induced transcriptional activator
  • ISGF-3
  • MGC59816
  • P113
  • signal transducer and activator of transcription 2
  • signal transducer and activator of transcription 2, 113kD
  • signal transducer and activator of transcription 2, 113kDa
  • STAT113
  • STAT2

Background

STAT2 (signal transducer and activator of transcription 2) is a 113 kDa member of the STAT family of cytoplasmic transcription factors. STAT members generally mediate cytokine, growth factor and hormone receptor signal transduction. STAT2 is associated with type I ( alpha - and beta -) interferon signaling. All STATs contain an N‑terminal oligomerization domain, a DNA-binding domain, and an SH2-association region. STAT2 is phosphorylated at Y689 by receptor-associated Janus kinases (JAKs) leading to STAT2 dimerization and subsequent translocation to the nucleus to activate gene transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for STAT2 (0)

There are no publications for STAT2.
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Reviews for STAT2 (0)

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FAQs for STAT2 (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STAT2
Entrez