STAT1 Antibody

Images

 
Western Blot: STAT1 Antibody [NB100-82206] - Analysis of extracts from Hela, A431 and JK cells using STAT1(Ab-701) antibody
Immunohistochemistry: STAT1 Antibody [NB100-82206] - Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT1 (Ab-701) antibody.

Product Details

Summary
Product Discontinued
View other related STAT1 Primary Antibodies

Order Details


    • Catalog Number
      NB100-82206
    • Availability
      Product Discontinued

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STAT1 Antibody Summary

Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human STAT1 around aa. 701(T-G-Y-I-K).
Specificity
STAT1 (specific to a.a. 701) detects endogenous levels of total STAT1 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
STAT1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Theoretical MW
91 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol.
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for STAT1 Antibody

  • CANDF7
  • DKFZp686B04100
  • ISGF-3
  • ISGF-3,91kD
  • signal transducer and activator of transcription 1, 91kDa
  • signal transducer and activator of transcription-1
  • STAT1
  • STAT91

Background

STATs (signal transducers and activators of transcription) were originally discovered as two proteins (STAT1 and STAT2) which were involved in interferon alpha (IFN alpha) and IFN gamma signal transduction. Since then, several additional STAT proteins have been identified (STAT3, 4, 5a, 5b, and 6). STATs undergo tyrosine phosphorylation in response to growth factor or cytokine signaling. This phosphorylation results in dimerization and translocation of STAT proteins to the nucleus. In some cases this process is mediated by JAK Kinases (Janus Kinases 1, 2, and 3). For maximum activation of these proteins, phosphorylation at specific tyrosine and serine residues may be required in STAT1 alpha, 3, 4, and 5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional STAT1 Products

Bioinformatics Tool for STAT1 Antibody (NB100-82206)

Discover related pathways, diseases and genes to STAT1 Antibody (NB100-82206). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for STAT1 Antibody (NB100-82206)

Discover more about diseases related to STAT1 Antibody (NB100-82206).
 

Pathways for STAT1 Antibody (NB100-82206)

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PTMs for STAT1 Antibody (NB100-82206)

Learn more about PTMs related to STAT1 Antibody (NB100-82206).

Blogs on STAT1.

Using a STAT3 antibody in chromatin immunoprecipitation (ChIP)
Signal transducer and activator of transcription 3 (STAT3) is an important oncogenic transcriptional factor that mediates tumor induced immune suppression.  Specifically, STAT3 transmits signals from cytokines and growth factor receptors in the pla...  Read full blog post.

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Bioinformatics

Gene Symbol STAT1
Entrez
Uniprot