STAT1 Antibody (9B12)

Images

 
Western Blot: STAT1 Antibody (9B12) [NBP1-48010] Analysis of extracts (35ug) from 9 different cell lines by usin g anti-STAT1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; ...read more
Western Blot: STAT1 Antibody (9B12) [NBP1-48010] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STAT1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-48010
    • Availability
      Product Discontinued

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STAT1 Antibody (9B12) Summary

Immunogen
Protein expressed in 293T cell transfected with human STAT1 expression vector
Specificity
This antibody is specific for Homo sapiens signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant beta.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
STAT1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000-2000

Reactivity Notes

Human, Canine, Primate

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for STAT1 Antibody (9B12)

  • CANDF7
  • DKFZp686B04100
  • ISGF-3
  • ISGF-3,91kD
  • signal transducer and activator of transcription 1, 91kDa
  • signal transducer and activator of transcription-1
  • STAT1
  • STAT91

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for STAT1 Antibody (NBP1-48010)

Discover related pathways, diseases and genes to STAT1 Antibody (NBP1-48010). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for STAT1 Antibody (NBP1-48010)

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Pathways for STAT1 Antibody (NBP1-48010)

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PTMs for STAT1 Antibody (NBP1-48010)

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Research Areas for STAT1 Antibody (NBP1-48010)

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Blogs on STAT1.

Using a STAT3 antibody in chromatin immunoprecipitation (ChIP)
Signal transducer and activator of transcription 3 (STAT3) is an important oncogenic transcriptional factor that mediates tumor induced immune suppression.  Specifically, STAT3 transmits signals from cytokines and growth factor receptors in the pla...  Read full blog post.

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Bioinformatics

Gene Symbol STAT1
Entrez