STAM-1 Antibody

Images

 
Western Blot: STAM-1 Antibody [NBP1-31243] - Sample (30 ug of whole cell lysate) A:H1299 7.5% SDS PAGE, antibody diluted at 1:3000.
Immunohistochemistry-Paraffin: STAM-1 Antibody [NBP1-31243] - Paraffin-embedded AdCA xenograft, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

STAM-1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human STAM. The exact sequence is proprietary.
Localization
Cytoplasm (Probable), Early endosome membrane, Peripheral membrane protein, Cytoplasmic side
Predicted Species
Mouse (96%), Rat (96%), Bovine (97%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STAM
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
59 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Zebrafish (87%), Xenopus laevis (88%),

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for STAM-1 Antibody

  • DKFZp686J2352
  • HSE1 Homolog
  • signal transducing adapter molecule 1
  • signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
  • STAM
  • STAM1
  • STAM-1
  • STAM1STAM-1

Background

This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STAM
Entrez