ST2/IL-1 R4 Antibody

Images

 
Western Blot: ST2/IL-1 R4 Antibody [NBP1-77148] - Analysis in 293 cell lysate with antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry: ST2/IL-1 R4 Antibody [NBP1-77148] - ST2 in human lung cancer tissue with ST2 antibody at 5 ug/ml.
Immunohistochemistry-Paraffin: ST2/IL-1 R4 Antibody [NBP1-77148] - Mouse kidney tissue with ST2 antibody at 2 ug/ml.
Immunohistochemistry: ST2/IL-1 R4 Antibody [NBP1-77148] - Staining of human liver tissue with antibody at 5 ug/mL.
Immunohistochemistry-Paraffin: ST2/IL-1 R4 Antibody [NBP1-77148] - Mouse kidney tissue.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

ST2/IL-1 R4 Antibody Summary

Immunogen
Antibody was raised against a synthetic peptide corresponding to 16 amino acids at the amino-terminus of mouse ST2. This peptide is common to all three known ST2 isoforms. The immunogen is located within amino acids 40 - 90 of ST2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ST2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-2 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 2 ug/mL
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 2 ug/ml
Application Notes
ST2 antibody can be used for the detection of ST2 by Western blot at 1 to 2 mg/ml. Mouse kidney cell lysate can be used as positive control. Anti-ST2 is human and mouse reactive.
Control Peptide
ST2/IL-1 R4 Peptide (NBP1-77148PEP)
Publications
Read Publications using NBP1-77148.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ST2/IL-1 R4 Antibody

  • DER4
  • Fit-1
  • IL-1 R4
  • IL1R4
  • IL-1R4
  • IL-1RL1
  • IL-33R
  • Ly84
  • ST2
  • ST2L
  • ST2V
  • suppression of tumorigenicity 2
  • T1

Background

ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ST2/IL-1 R4 Antibody (NBP1-77148)(4)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Diseases for ST2/IL-1 R4 Antibody (NBP1-77148)

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Bioinformatics

Gene Symbol ST2
Entrez
Uniprot