ST2/IL-1 R4 Antibody

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Western Blot: ST2/IL-1 R4 Antibody [NBP1-32834] - (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE; antibody diluted at 1:500

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-32834
    • Availability
      Product Discontinued

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ST2/IL-1 R4 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human ST2. The exact sequence is proprietary.
Localization
Isoform C: Cell membrane, Isoform B: Secreted, Cell membrane, Single-pass type I membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ST2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ST2/IL-1 R4 Antibody

  • DER4
  • Fit-1
  • IL-1 R4
  • IL1R4
  • IL-1R4
  • IL-1RL1
  • IL-33R
  • Ly84
  • ST2
  • ST2L
  • ST2V
  • suppression of tumorigenicity 2
  • T1

Background

ST2 is a member of a superfamily containing the Interleukin 1 (IL1) receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL1 receptor and Toll-like receptor 4 (TLR4) signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional ST2/IL-1 R4 Products

Bioinformatics Tool for ST2/IL-1 R4 Antibody (NBP1-32834)

Discover related pathways, diseases and genes to ST2/IL-1 R4 Antibody (NBP1-32834). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for ST2/IL-1 R4 Antibody (NBP1-32834)

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Pathways for ST2/IL-1 R4 Antibody (NBP1-32834)

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PTMs for ST2/IL-1 R4 Antibody (NBP1-32834)

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol ST2
Entrez