Recombinant Human SRP14 Protein

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SDS-Page: SRP14 Protein [NBP1-50885]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human SRP14 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-136 of Human SRP14

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMVLLES EQFLTELTRL FQKCRTSGSV YITLKKYDGR TKPIPKKGTV EGFEPADNKC LLRATDGKKK ISTVVSSKEV NKFQMAYSNL LRANMDGLKK RDKKNKTKKT KAAAAAAAAA PAAAATAATT AATTAATAAQ

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
SRP14
Purity
>85%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
17.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>85%, by SDS-PAGE

Alternate Names for Recombinant Human SRP14 Protein

  • ALURBP
  • MGC14326,18 kDa Alu RNA-binding protein
  • signal recognition particle 14 kDa protein
  • signal recognition particle 14kD (homologous Alu RNA-binding protein)
  • signal recognition particle 14kDa (homologous Alu RNA binding protein)

Background

SRP14 is a ribonucleoprotein complex that mediates the targeting of proteins to the endoplasmic reticulum. The "Alu domain" of SRP comprises the heterodimer of the SRP9 and SRP14 proteins, which are bound to the 5' and 3' terminal sequences of SRP RNA. SRP9/14 binding may be crucial to the transcription, maturation, nucleolus localization and transport of SRP RNA. Recombinant human SRP14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol SRP14