SP110 Antibody

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Immunohistochemistry-Paraffin: SP110 Antibody [NBP1-52532] - Analysis of anti-SP110 antibody with human spleen at concentration 3.75 ug/ml.
Immunohistochemistry-Paraffin: SP110 Antibody [NBP1-52532] - Analysis of anti-SP110 antibody with human tonsil at concentration 3.75 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

SP110 Antibody Summary

Immunogen
Synthetic peptide C-PQEVSSTPSDKKGKK from an internal region of human SP110 (NP_004500.3; NP_004501.3; NP_536349.2).
Specificity
Human SP110. This antibody is expected to recognize all three reported isoforms (NP_004500.3; NP_004501.3; NP_536349.2).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SP110
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 3.75 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (92%), Marmoset (92%), Gibbon (87%).

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
TBS (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SP110 Antibody

  • FLJ22835
  • IFI41
  • IFI75
  • interferon-induced protein 41, 30kD
  • Interferon-induced protein 41/75
  • interferon-induced protein 75, 52kD
  • IPR1
  • phosphoprotein 41
  • phosphoprotein 75
  • SP110 nuclear body protein
  • Speckled 110 kDa
  • Transcriptional coactivator Sp110
  • VODI

Background

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq]. Transcript Variant: This variant (b) uses an alternate exon for the 3' coding region and 3' UTR, as compared to variant c. The encoded protein (isoform b) has a shorter and distinct C-terminus and lacks the bromodomain when it is compared to isoform c. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SP110 Antibody (NBP1-52532) (0)

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Bioinformatics

Gene Symbol SP110
Entrez
Uniprot