SP110 Antibody Summary
Synthetic peptide C-PQEVSSTPSDKKGKK from an internal region of human SP110 (NP_004500.3; NP_004501.3; NP_536349.2).
Human SP110. This antibody is expected to recognize all three reported isoforms (NP_004500.3; NP_004501.3; NP_536349.2).
Immunogen affinity purified
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- Immunohistochemistry-Paraffin 3.75 ug/ml
Predicted cross-reactivity based on sequence identity: Gorilla (92%), Marmoset (92%), Gibbon (87%).
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
TBS (pH 7.3) and 0.5% BSA
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for SP110 Antibody
- interferon-induced protein 41, 30kD
- Interferon-induced protein 41/75
- interferon-induced protein 75, 52kD
- phosphoprotein 41
- phosphoprotein 75
- SP110 nuclear body protein
- Speckled 110 kDa
- Transcriptional coactivator Sp110
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq]. Transcript Variant: This variant (b) uses an alternate exon for the 3' coding region and 3' UTR, as compared to variant c. The encoded protein (isoform b) has a shorter and distinct C-terminus and lacks the bromodomain when it is compared to isoform c. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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