Somatostatin R2/SSTR2 Antibody

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Immunohistochemistry-Paraffin: Somatostatin R2/SSTR2 Antibody [NLS1001] - Analysis of anti-SSTR2 antibody with human pancreas, islet of langerhans at 16 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Somatostatin R2/SSTR2 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from C-terminus of human SSTR2.
Localization
Cell Membrane
Specificity
Somatostatin Receptor Type 2
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SSTR2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 16 ug/ml

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Somatostatin R2/SSTR2 Antibody

  • Smstr2
  • Somatostatin R2
  • somatostatin receptor 2
  • somatostatin receptor type 2
  • SomatostatinR2
  • SRIF-1
  • SS2R
  • SS-2-R
  • SS2-R
  • SST2
  • SSTR2

Background

SST2 is a Somatostatin receptor. Somatostatin negatively regulates the growth of various normal and tumour cells via five somatostatin receptors. Somatostatin receptors are expressed by a large variety of human tumors, and the predominant expression of SST2 receptors in tumor tissues forms the basis for the successful application of SST2-preferring agonists in the treatment of patients with GH-secreting pituitary adenomas, as well as in patients with carcinoid or islet cell tumors. The SST2 receptor exists as two splice variants that differ in length and composition of their intracellular carboxy termini. SST2 is the only member of the somatostatin receptor family that contains introns. SST2 expression has been reported in adrenal, aorta, brain, breast, eye, gastrointestinal tract, pancreas, prostate, spinal cord, and thyroid. ESTs have been isolated from brain, eye, head/neck, kidney, lymph node, pineal, and prostate libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SSTR2
Entrez