SOCS-3 Antibody (OTI3B8)


Western Blot: SOCS3 Antibody (3B8) [NBP2-00864] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SOCS3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates more
Immunocytochemistry/ Immunofluorescence: SOCS3 Antibody (3B8) [NBP2-00864] Staining of COS7 cells transiently transfected by pCMV6-ENTRY SOCS3.
Flow Cytometry: SOCS3 Antibody (3B8) [NBP2-00864] - Analysis of Jurkat cells, using anti-SOCS3 antibody, (Red), compared to a nonspecific negative control antibody (Blue).
Flow Cytometry: SOCS3 Antibody (3B8) [NBP2-00864] - Analysis of Hela cells, using anti-SOCS3 antibody, (Red), compared to a nonspecific negative control antibody (Blue).

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SOCS-3 Antibody (OTI3B8) Summary

Full length recombinant protein of human SOCS-3 (NP_003946) produced in HEK293T cells.
Immunogen affinity purified
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  • Western Blot 1:2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
Theoretical MW
24.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes


Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
0.02% Sodium Azide
Immunogen affinity purified

Alternate Names for SOCS-3 Antibody (OTI3B8)

  • ATOD4
  • CIS3
  • CIS3CIS-3
  • Cish3
  • cytokine-induced SH2 protein 3
  • Cytokine-inducible SH2 protein 3
  • SOCS3
  • SOCS-3
  • SOCS-3STAT-induced STAT inhibitor 3
  • SSI-3
  • SSI-3ATOD4
  • SSI3MGC71791
  • suppressor of cytokine signaling 3


This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq].


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Gene Symbol SOCS3