SOCS-1 Antibody (4H1)


Immunoprecipitation: SOCS-1 Antibody (4H1) [NBP1-54563]

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, IP
1 mg/ml

Order Details

SOCS-1 Antibody (4H1) Summary

Recombinant mouse SOCS-1 (2-78 a.a.)
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2) and 50% Glycerol
No Preservative
1 mg/ml
Protein A purified


  • Western Blot 1:100-1:2000
  • Immunoprecipitation 1:10-1:500

Reactivity Notes

Human, Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Alternate Names for SOCS-1 Antibody (4H1)

  • CIS1
  • Cish1
  • JAB
  • JABTec-interacting protein 3
  • JAK binding protein
  • JAK-binding protein
  • SOCS1
  • SOCS-1CIS1
  • SSI-1
  • SSI-1CISH1
  • SSI1cytokine-inducible SH2 protein 1
  • STAT induced SH3 protein 1
  • STAT-induced STAT inhibitor 1
  • suppressor of cytokine signaling 1
  • TIP3
  • TIP-3
  • TIP3Cish1


The SOCS (suppressor of cytokine signaling) gene family consists of a group of proteins that negatively regulate cytokine signal transduction. The SOCS family proteins contain a central SH2 domain and a carboxy-terminal region termed the "SOCS box." The SOCS-1 (also called SSI-1 and JAB), SOCS-2 (also called SSI-2 and CIS2) and SOC-3 (also called SSI-3 and CIS3) genes are known to be upregulated by IL-6 and other cytokines. SOCS-4, SOCS-5, SOCS-6 and SOCS-7 were identified by their sequence homology with the SOCS box. CIS (for cytokine-inducible SH2-containing protein) is also a member of the SOCS family.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for SOCS-1 Antibody (NBP1-54563). (Showing 1 - 1 of 1 FAQ).

  1. We would like to know if you have checked whether this antibody can be used for flow cytometry and how you have checked their specificity?
    • SOCS1 Antibody (4H1) (NBP1-54563) has not yet been tested in flow cytometry, so we cannot guarantee that it will work in this application. However, if you did use this product in flow, you would be eligible for our Innovator's Reward Program, where in return for sharing your findings with us (whether the antibody proved suitable or not) by completing a review, we would give you a voucher code for the cost of the product; please see here for details: Innovator's Reward program. I do not think specificity testing has been carried out on NBP1-54563, but I have performed UniProt Blast sequence analyses of the exact immunogen sequence for an indication of likely cross-reactivity. The results were: Mouse: 100% match to SOCS1. No significant similarity to any other proteins detected. Human: 90% homology to SOCS1. 48% sequence similarity (a very low percentage) with taperin.

Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol SOCS1

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