SOCS-1 Antibody (4H1)

Images

 
There are currently no images for SOCS-1 Antibody (NBP1-54563).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clone
4H1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

SOCS-1 Antibody (4H1) Summary

Immunogen
Recombinant mouse SOCS-1 (2-78 a.a.)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SOCS1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 50% Glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for SOCS-1 Antibody (4H1)

  • CIS1
  • Cish1
  • JAB
  • JABTec-interacting protein 3
  • JAK binding protein
  • JAK-binding protein
  • SOCS1
  • SOCS-1
  • SOCS-1CIS1
  • SSI-1
  • SSI-1CISH1
  • SSI1cytokine-inducible SH2 protein 1
  • STAT induced SH3 protein 1
  • STAT-induced STAT inhibitor 1
  • suppressor of cytokine signaling 1
  • TIP3
  • TIP-3
  • TIP3Cish1

Background

The SOCS (suppressor of cytokine signaling) gene family consists of a group of proteins that negatively regulate cytokine signal transduction. The SOCS family proteins contain a central SH2 domain and a carboxy-terminal region termed the "SOCS box." The SOCS-1 (also called SSI-1 and JAB), SOCS-2 (also called SSI-2 and CIS2) and SOC-3 (also called SSI-3 and CIS3) genes are known to be upregulated by IL-6 and other cytokines. SOCS-4, SOCS-5, SOCS-6 and SOCS-7 were identified by their sequence homology with the SOCS box. CIS (for cytokine-inducible SH2-containing protein) is also a member of the SOCS family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-30943
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-27210
Species: Hu, Fe, Pm
Applications: WB, IHC-P
AF2988
Species: Mu, Rt
Applications: WB
AF2894
Species: Hu, Mu
Applications: WB, Simple Western, CyTOF-ready, ICFlow
NB400-141
Species: Hu, Mu, Ha
Applications: WB, ICC/IF, IP
NBP2-22471
Species: Hu, Mu, Rt, Mk, Pm
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
AF4979
Species: Hu
Applications: WB
MAB4260
Species: Hu, Mu, Rt
Applications: WB, IHC, CyTOF-ready, ICC, ICFlow
AF1584
Species: Hu, Mu
Applications: WB, Simple Western, IP, CyTOF-ready, ICC, ICFlow
NBP2-00622
Species: Hu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NB200-106
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
NB100-56566
Species: Hu, Mu, Rt
Applications: WB, ChIP, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, CyTOF-ready, Flow-CS, Flow-IC
NBP2-25241
Species: Hu, Mu
Applications: WB, ICC/IF, IP

Publications for SOCS-1 Antibody (NBP1-54563) (0)

There are no publications for SOCS-1 Antibody (NBP1-54563).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for SOCS-1 Antibody (NBP1-54563) (0)

There are no reviews for SOCS-1 Antibody (NBP1-54563). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for SOCS-1 Antibody (NBP1-54563). (Showing 1 - 1 of 1 FAQ).

  1. We would like to know if you have checked whether this antibody can be used for flow cytometry and how you have checked their specificity?
    • SOCS1 Antibody (4H1) (NBP1-54563) has not yet been tested in flow cytometry, so we cannot guarantee that it will work in this application. However, if you did use this product in flow, you would be eligible for our Innovator's Reward Program, where in return for sharing your findings with us (whether the antibody proved suitable or not) by completing a review, we would give you a voucher code for the cost of the product; please see here for details: Innovator's Reward program. I do not think specificity testing has been carried out on NBP1-54563, but I have performed UniProt Blast sequence analyses of the exact immunogen sequence for an indication of likely cross-reactivity. The results were: Mouse: 100% match to SOCS1. No significant similarity to any other proteins detected. Human: 90% homology to SOCS1. 48% sequence similarity (a very low percentage) with taperin.

Secondary Antibodies

 

Isotype Controls

Additional SOCS-1 Products

Bioinformatics Tool for SOCS-1 Antibody (NBP1-54563)

Discover related pathways, diseases and genes to SOCS-1 Antibody (NBP1-54563). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for SOCS-1 Antibody (NBP1-54563)

Discover more about diseases related to SOCS-1 Antibody (NBP1-54563).
 

Pathways for SOCS-1 Antibody (NBP1-54563)

View related products by pathway.

PTMs for SOCS-1 Antibody (NBP1-54563)

Learn more about PTMs related to SOCS-1 Antibody (NBP1-54563).
 

Research Areas for SOCS-1 Antibody (NBP1-54563)

Find related products by research area.

Blogs on SOCS-1

There are no specific blogs for SOCS-1, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our SOCS-1 Antibody (4H1) and receive a gift card or discount.

Bioinformatics

Gene Symbol SOCS1
Entrez