SNX15 Antibody

Immunoprecipitation: SNX15 Antibody [NBP2-59133] - Detection of human SNX15 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SNX15 antibody NBP2-59133 used for IP at 8 ul per reaction. SNX15 was also immunoprecipitated by rabbit anti-SNX15 antibody. Detection: Chemiluminescence with an exposure time of 3 minutes.

Product Discontinued

SNX15 Antibody Summary

• Immunogen: Maps to a region between 225 and 275
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SNX15
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 8-15 ul/mg lysate
• Application Notes: Western Blot Not recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: Tris-buffered Saline containing 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.4 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SNX15 Antibody

• clone iota unknown protein
• HSAF001435
• sorting nexin 15
• sorting nexin-15

Background

SNX15 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SNX15