SNF8 Antibody

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Western Blot: Vacuolar sorting protein SNF8 Antibody [NBP1-03424] - rat brain lysate using Rabbit antibody to internal part of Vacuolar sorting protein SNF8: whole serum at 1:1000 dilution. Pre-absorption of the ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-03424
    • Availability
      Product Discontinued

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SNF8 Antibody Summary

Immunogen
A synthetic peptide from the internal part of human Vacuolar-sorting protein SNF8 (EAP30, SNF8, ELL-associated protein of 30 kDa) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, mouse and xenopus.
Localization
subcellular location: cytoplasm. nucleus.
Specificity
SNF8.
Clonality
Polyclonal
Host
Rabbit
Gene
SNF8
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Positive Control
SNF8 Lysate (NBL1-16280)

Reactivity Notes

Mouse, Rat and Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute to desired concentration. Add glycerol (1:1) for additional stability.

Alternate Names for SNF8 Antibody

  • EAP30 subunit of ELL complex
  • EAP30hVps22
  • ELL-associated protein of 30 kDa
  • ESCRT-II complex subunit VPS22
  • SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
  • vacuolar-sorting protein SNF8
  • VPS22Dot3

Background

Component of the escrt-ii complex, which is required for multivesicular bodies (mvbs) formation and sorting of endosomal cargo proteins into mvbs. the mvb pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. the escrt-ii complex is probably involved in the recruitment of the escrt-iii complex. the escrt-ii complex may also play a role in transcription regulation by participating in derepression of transcription by rna polymerase ii, possibly via its interaction with ell.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SNF8
Entrez
Uniprot