Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Phosphate buffered saline (PBS) approx. pH 7.2.
0.05% Sodium Azide
Immunogen affinity purified
Western blot (WB)analyzes of p-Smad2 (S467) pAb in extracts from HepG2 treated with PMA 125ng/ml 15'Immunohistochemistry (IHC) analyzes of p-Smad2 (S467) pAb in paraffin-embedded human breast carcinoma tissue The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publication using NBP1-51391 in the following applications:
JV18-1SMAD, mothers against DPP homolog 2 (Drosophila)
MAD homolog 2
Mad protein homolog
Mad, mothers against decapentaplegic homolog 2
Mad-related protein 2
mother against DPP homolog 2
mothers against decapentaplegic homolog 2
Mothers against DPP homolog 2
Sma- and Mad-related protein 2
SMAD family member 2MAD, mothers against decapentaplegic homolog 2 (Drosophila)
SMAD, mothers against DPP homolog 2
Smad proteins, the mammalian homologs of the Drosophila Mothers againstdpp (Mad) have been implicated as downstream effectors of TGF beta/BMPsignaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalianSmad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4function while Smad2 (also designated Madr2 or JV18-1) and Smad3 areinvolved inTGF beta and activin-mediated growth modulation. Smad4 (also designatedDPC4) has been shown to mediate all of the above activities throughinteraction with various Smad family members. Smad6 and Smad7 regulatethe response to activin/TGF beta signaling by interfering with TGF beta-mediatedphosphorylation of other Smad family members.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.