SMAC/Diablo Antibody

Images

 
Western Blot: SMAC/Diablo Antibody [H00056616-B01] - Analysis of DIABLO expression in human kidney.
Western Blot: SMAC/Diablo Antibody [H00056616-B01] - Analysis of DIABLO expression in transfected 293T cell line. Lane 1: DIABLO transfected lysate (26.29 KDa). Lane 2: Non-transfected lysate.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00056616-B01
    • Availability
      Product Discontinued

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SMAC/Diablo Antibody Summary

Immunogen
DIABLO (NP_063940, 1 a.a. ~ 239 a.a) full-length human protein.MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED
Specificity
DIABLO - diablo homolog (Drosophila),
Clonality
Polyclonal
Host
Mouse
Gene
DIABLO
Purity
Unpurified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against transfected lysate and tissue lysate for Western Blot. Has also been used for ELISA.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Serum
Preservative
No Preservative
Purity
Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SMAC/Diablo Antibody

  • 0610041G12Rik
  • Diablo
  • diablo, IAP-binding mitochondrial protein
  • Direct IAP-binding protein with low pI
  • mitochondrial Smac protein
  • Second mitochondria-derived activator of caspase
  • SMAC
  • SMACmitochondrial

Background

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SMAC/Diablo Antibody (H00056616-B01) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional SMAC/Diablo Products

Bioinformatics Tool for SMAC/Diablo Antibody (H00056616-B01)

Discover related pathways, diseases and genes to SMAC/Diablo Antibody (H00056616-B01). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for SMAC/Diablo Antibody (H00056616-B01)

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Pathways for SMAC/Diablo Antibody (H00056616-B01)

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PTMs for SMAC/Diablo Antibody (H00056616-B01)

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Research Areas for SMAC/Diablo Antibody (H00056616-B01)

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Blogs on SMAC/Diablo.

Apoptosis and Necroptosis Part II: Inhibitors of apoptosis proteins (IAPs); Key regulators of the balance between necroptosis, apoptosis and survival
In the first installment of this two-part blog post titled "Apoptosis and Necroptosis: Important factors to identify both types of programmed cell death", the mechanisms by which cell death occurs and ways to identify these pathways were...  Read full blog post.

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Bioinformatics

Gene Symbol DIABLO
Entrez
Uniprot