Siglec-2/CD22 Antibody (Bu59) [FITC]



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Siglec-2/CD22 Antibody (Bu59) [FITC] Summary

Made to Human CD22
NB100-63586 recognizes human CD22, a 130/140kD cell surface glycoprotein which is expressed by cells of B-lymphocyte lineage. CD22 is differentially expressed during B cell maturation. Initially, CD22 is expressed in the cytoplasm of pro-B and pre-B cells and then on the cell surface of mature B cells. CD22 expression is lost upon terminal differentiation to plasma cells. CD22 functions as an adhesion receptor, for leucocytes and erythrocytes, and a signalling molecule which may play a role in B-cell activation.
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
FITC (A=495, E=519)
PBS (pH 7.4) and 1.0% BSA
0.09% Sodium Azide
0.1 mg/ml
Protein G purified

Reactivity Notes

Reacts with Human.


CD22 is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140kD. It is expressed in both the cytoplasm and cell membrane of B lymphocytes. CD22 antigen appears early in B cell lymphocyte differentiation at approximately the same stage as the CD19 antigen. Unlike other B cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias. CD22 is also strongly expressed in hairy cell leukemia. There are two different isoforms of CD22. It exists predominantly as a monomer of the beta isoform but can also be found as a heterodimer composed of the beta isoform and a second, shorter isoform (CD22 alpha).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Siglec-2/CD22 Antibody (NB100-63587). (Showing 1 - 1 of 1 FAQ).

  1. I am interested in buying a CD22 antibody for fluorescence microscopy and FACS I red on your web page that you also offer to label your antibodies, if required, is that correct?
    • We do have the ability to perform custom conjugations on certain antibodies, including some to the CD22 protein. If you send me the conjugate you are interested in I can provide you with a quote.

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Gene Symbol CD22

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