SHP-2/PTPN11 Antibody - Pre-diluted

Images

 
There are currently no images for PTPN11/SHP2 Antibody (NBP1-36472).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Pre-diluted

Order Details

SHP-2/PTPN11 Antibody - Pre-diluted Summary

Immunogen
Synthetic peptide corresponding to aa 576-593 of human SH-PTP2 protein.
Specificity
This product is specific for SH-PTP2
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPN11
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin Neat

Reactivity Notes

This product is specific for Human, Mouse, Rat.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Prediluted antibody
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for SHP-2/PTPN11 Antibody - Pre-diluted

  • BPTP3
  • EC 3.1.3.48
  • MGC14433
  • protein tyrosine phosphatase, non-receptor type 11
  • protein tyrosine phosphatase-2
  • Protein-tyrosine phosphatase 1D
  • Protein-tyrosine phosphatase 2C
  • PTP1D
  • PTP-1D
  • PTP2C
  • PTP-2C
  • PTP2CNS1
  • PTPN11
  • SHP2
  • SHP-2
  • SHP2CFC
  • SHPTP2
  • SH-PTP2
  • SH-PTP2Noonan syndrome 1
  • SH-PTP3
  • tyrosine-protein phosphatase non-receptor type 11

Background

SHP-2 (also called PTP2C, SH-PTP2, PTP1D, SH-PTP3, Syp and PTPN11) is a protein tyrosine phosphatase (PTP) expressed in most cell types (unlike SHP-1), (1). SHP-2 is involved in t the signal transduction stimulated by EGF, PDGF and Insulin. After cell stimulation, SHP-2 (as well as SHP-1), translocates from cytosol to the plasma membrane and binds to tyrosine-phosphorylated receptors through their SH2 domains, becoming activated in the process (2). When phosphorylated, SHP-2 has been shown to bind Grb2, EGFR, PDGFR, IRS-1 via its SH2 domain (3). Over expression of SHP-2 leads to Juvenile Myelo-monocytic Leukemia and Noonan syndrome (4-5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-83276
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
AF2685
Species: Hu
Applications: WB, Simple Western, IHC
H00003845-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IP
NBP2-22203
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
AF1638
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC
MAB38461
Species: Hu
Applications: WB, IHC
AF467
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, ICC
AF2988
Species: Mu, Rt
Applications: WB
AF-386-PB
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
AF3978
Species: Hu, Mu, Rt
Applications: WB, IHC
MAB4540
Species: Hu, Mu, Rt
Applications: WB, IHC
NB100-56749
Species: Hu, Mu
Applications: WB, IHC, IHC-P
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
NBP1-36472
Species: Hu, Mu, Rt
Applications: IHC, IHC-P

Publications for PTPN11/SHP2 Antibody (NBP1-36472) (0)

There are no publications for PTPN11/SHP2 Antibody (NBP1-36472).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PTPN11/SHP2 Antibody (NBP1-36472) (0)

There are no reviews for PTPN11/SHP2 Antibody (NBP1-36472). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for PTPN11/SHP2 Antibody (NBP1-36472) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional SHP-2/PTPN11 Products

Bioinformatics Tool for PTPN11/SHP2 Antibody (NBP1-36472)

Discover related pathways, diseases and genes to PTPN11/SHP2 Antibody (NBP1-36472). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PTPN11/SHP2 Antibody (NBP1-36472)

Discover more about diseases related to PTPN11/SHP2 Antibody (NBP1-36472).
 

Pathways for PTPN11/SHP2 Antibody (NBP1-36472)

View related products by pathway.

PTMs for PTPN11/SHP2 Antibody (NBP1-36472)

Learn more about PTMs related to PTPN11/SHP2 Antibody (NBP1-36472).
 

Research Areas for PTPN11/SHP2 Antibody (NBP1-36472)

Find related products by research area.

Blogs on SHP-2/PTPN11

There are no specific blogs for SHP-2/PTPN11, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our SHP-2/PTPN11 Antibody - Pre-diluted and receive a gift card or discount.

Bioinformatics

Gene Symbol PTPN11
Entrez