SET Antibody

Images

 
Western Blot: SET Antibody [NBP1-19600] - extracts from HeLa cells.
Immunohistochemistry-Paraffin: SET Antibody [NBP1-19600] - Human brain carcinoma tissue.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-19600
    • Availability
      Product Discontinued

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SET Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 280-336 of Human TAF I p48.
Clonality
Polyclonal
Host
Rabbit
Gene
SET
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analyzes of TAF I p48 (R318) pAb in extracts from HeLa cells.
Immunohistochemistry (IHC) analyzes of TAF I p48 (R318) pAb in paraffin-embedded human brain carcinoma tissue.
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SET Antibody

  • 2PP2A
  • HLA-DR-associated protein II
  • I2PP2A
  • I-2PP2A
  • IGAAD
  • Inhibitor of granzyme A-activated DNase
  • inhibitor-2 of protein phosphatase-2A
  • IPP2A2
  • PHAPIITAF-I
  • Phosphatase 2A inhibitor I2PP2A
  • protein phosphatase type 2A inhibitor
  • protein SET
  • SET nuclear oncogene
  • SET translocation (myeloid leukemia-associated)
  • TAF-IBETA
  • Template-activating factor I
  • Template-Activating Factor-I, chromatin remodelling factor

Background

For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter and RNA polymerase-specific complexes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SET
Entrez