Serpin E1/PAI-1 Antibody (3F2)

Images

 
Western Blot: Serpin E1/PAI-1 Antibody (3F2) [H00005054-M01] - Analysis of SERPINE1 expression in transfected 293T cell line by SERPINE1 monoclonal antibody (M01), clone 3F2.Lane 1: SERPINE1 transfected lysate(45.1 ...read more
Immunoprecipitation: Serpin E1/PAI-1 Antibody (3F2) [H00005054-M01] - Analysis of SERPINE1 transfected lysate using anti-SERPINE1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SERPINE1 MaxPab ...read more
Sandwich ELISA: Serpin E1/PAI-1 Antibody (3F2) [H00005054-M01] - Detection limit for recombinant GST tagged SERPINE1 is approximately 0.3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IP
Clone
3F2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Serpin E1/PAI-1 Antibody (3F2) Summary

Immunogen
SERPINE1 (NP_000593, 86 a.a. - 185 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTR
Localization
Secreted
Specificity
SERPINE1 - serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SERPINE1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunoprecipitation
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.
Publications
Read Publication using H00005054-M01.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Serpin E1/PAI-1 Antibody (3F2)

  • Endothelial plasminogen activator inhibitor
  • Nexin
  • PAI1
  • PAI-1
  • PAI1PAI-1
  • PAISerpin E1
  • PLANH1
  • PLANH1plasminogen activator inhibitor 1
  • serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1
  • Serpin E1
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1

Background

PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type palsminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Serpin E1/PAI-1 Antibody (H00005054-M01)(1)

We have publications tested in 1 confirmed species: Human.


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Bioinformatics

Gene Symbol SERPINE1
Entrez
OMIM
Uniprot