Serpin B6 Antibody (3H3)

Images

 
Western Blot: SerpinB6 Antibody (3H3) [NBP2-01822] Analysis of extracts (35ug) from 9 different cell lines by using anti-SerpinB6 monoclonal antibody.
Immunocytochemistry/ Immunofluorescence: SerpinB6 Antibody (3H3) [NBP2-01822] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY SerpinB6.
Flow Cytometry: SerpinB6 Antibody (3H3) [NBP2-01822] - Analysis of Jurkat cells, using anti-SerpinB6 antibody, (Red), compared to a nonspecific negative control antibody (Blue).
Western Blot: SerpinB6 Antibody (3H3) [NBP2-01822] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SerpinB6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell ...read more
Flow Cytometry: SerpinB6 Antibody (3H3) [NBP2-01822] - Analysis of Hela cells, using anti-SerpinB6 antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-01822
    • Availability
      Product Discontinued

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Serpin B6 Antibody (3H3) Summary

Immunogen
Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SERPINB6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100

Reactivity Notes

Human, Monkey, Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Serpin B6 Antibody (3H3)

  • CAP
  • CAPMGC111370
  • Cytoplasmic antiproteinase
  • deafness, autosomal recessive 91
  • DFNB91
  • Peptidase inhibitor 6
  • PI6
  • PI-6
  • PI6MSTP057
  • Placental thrombin inhibitor
  • protease inhibitor 6 (placental thrombin inhibitor)
  • PTI
  • PTIDKFZp686I04222
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6
  • Serpin B6
  • serpin peptidase inhibitor, clade B (ovalbumin), member 6
  • SPI3

Background

The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SERPINB6
Entrez