Seladin 1 Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

Seladin 1 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-DHCR24 full-length
Gene
DHCR24

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Seladin 1

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-DHCR24 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Seladin 1 Overexpression Lysate (Denatured)

  • 24-dehydrocholesterol reductaseNbla03646
  • DCE
  • desmosterol-to-cholesterol enzyme
  • Diminuto/dwarf1 homolog
  • EC 1.3.1.72
  • KIAA0018SELADIN1
  • seladin 1,3-beta-hydroxysterol delta-24-reductase
  • seladin-1
  • selective AD indicator 1,3 beta-hydroxysterol delta 24-reductase

Background

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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H00001718-T01
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Applications: WB

Publications for Seladin 1 Lysate (H00001718-T01) (0)

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Bioinformatics

Gene Symbol DHCR24