SEC61A Antibody

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Western Blot: SEC61A Antibody [NB120-15575] - Analysis of pig microsomes.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Ba, CaSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

SEC61A Antibody Summary

Immunogen
Synthetic peptide corresponding to residues C(13) V I L P E I Q K P E R K I Q F K E K(31) of canine SEC61 alpha.
Localization
Endoplasmic reticulum
Specificity
SEC61A
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SEC61A1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:20000
Application Notes
WB: Detects an approx. 38 kDa protein representing sec61 alpha from pig microsomes.
Publications
Read Publication using
NB120-15575 in the following applications:

  • WB
    1 publication

Reactivity Notes

Bacteria reactivity reported in scientific literature (PMID: 27821549).

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for SEC61A Antibody

  • HSEC61
  • protein transport protein SEC61 alpha subunit
  • protein transport protein Sec61 subunit alpha isoform 1
  • protein transport protein Sec61 subunit alpha
  • Sec61 alpha 1 subunit (S. cerevisiae)
  • Sec61 alpha-1
  • sec61 homolog
  • SEC61
  • SEC61A

Background

SEC61A belongs to the SECY/SEC61 alpha family. It has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum.The SEC61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. SEC61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. SEC61 alpha is a polytopic protein that has ten membrane-spanning loops. SEC61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SEC61A Antibody (NB120-15575)(1)

We have publications tested in 1 confirmed species: Bacteria.

We have publications tested in 1 application: WB.


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WB
(1)
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Bioinformatics

Gene Symbol SEC61A1
Entrez
Uniprot