SALL1 Antibody

• Reactivity: Hu, Mu
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

SALL1 Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence EKGQPSRPTKSKDAH-C corresponding to N-Terminus according to NP_002959.2, NP_001121364.1.
• Epitope: EKGQPSRPTKSKDAH-C
• Specificity: This antibody is expected to recognize both reported isoforms (NP_002959.2; NP_001121364.1).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SALL1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Blot: Preliminary experiments gave an approx. 100 kDa band in human brain (amygdala and substantia nigra) and mouse kidney lysates after 1 ug/ml antibody staining An approx. 140 kDa is observed (calculated MW of 140 kDa band according to human NP_002959.2 and mouse NP_067365.2, and 130 kDa band according to human NP_001121364.1). Please note that currently we cannot find an explanation in scientific literatures.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SALL1 Antibody

• HSAL1
• sal (Drosophila)-like 1
• SAL1
• Sal-1
• SALL1
• sal-like 1 (Drosophila)
• sal-like protein 1
• Spalt-like transcription factor 1
• Zinc finger protein 794
• Zinc finger protein SALL1
• Zinc finger protein Spalt-1
• ZNF794TBS

Background

The protein encoded by the SALL1 gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SALL1 Antibody (NBP1-52141)(1)

Publication using NBP1-52141

• Barry JS, Reddy MA. The association of an epibulbar dermoid and Duane syndrome in a patient with a SALL1 mutation (Townes-Brocks Syndrome). Ophthalmic Genet 2008-12-01 [PMID: 19005989]

Bioinformatics

• Gene Symbol: SALL1
• Entrez:
  • 6299(Human)
  • 58198(Mouse)
• Uniprot:
  • NP_002959.2(Human)