S1P3/EDG-3 Antibody

Images

 
Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NLS1031] - Anti-SIPR3 / EDG3 / S1P3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NLS1031] - Analysis of anti-EDG3 / S1P3 antibody with liver at 3 ug/ ml.
Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NLS1031] - Analysis of anti-EDG3 / S1P3 antibody with cells expressing vector only using this antibody at 3 ug/ ml.
Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NLS1031] - Analysis of anti-EDG3 / S1P3 antibody with transfected cells at 3 ug/ ml.
Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NLS1031] - Analysis of anti-EDG3 / S1P3 antibody with human kidney.

Product Details

Summary
Reactivity Hu, MkSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

S1P3/EDG-3 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from C-terminus of human EDG3 / S1P3.
Specificity
Human EDG3 / S1P3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TPRX1 (56%).
Predicted Species
Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
S1PR3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (94%), Elephant (94%), Bovine (89%), Gibbon (83%), Rabbit (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for S1P3/EDG-3 Antibody

  • EDG3
  • EDG-3
  • EDG3FLJ37523
  • Endothelial differentiation G-protein coupled receptor 3
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 3
  • FLJ93220
  • G protein-coupled receptor, endothelial differentiation gene-3
  • LPB3
  • MGC71696
  • S1P receptor 3
  • S1P receptor EDG3
  • S1P receptor Edg-3
  • S1P3
  • S1PR3
  • sphingosine 1-phosphate receptor 3
  • Sphingosine 1-phosphate receptor Edg-3
  • sphingosine-1-phosphate receptor 3

Background

EDG3, a Lysophospholipid/Lysosphingolipid Receptor, binds the vasoconstrictor sphingosine-1-phosphate and activates transcription of serum response element-driven reporter genes. EDG3 may regulate angiogenesis and vascular endothelial cell functions. EDG3 has been reported in all tissues, with highest levels in heart, placenta, kidney, and liver. ESTs have been isolated from placenta and germ cell tumor libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol S1PR3
Entrez