S1P3/EDG-3 Antibody

Images

 
Western Blot: S1P3/EDG-3 Antibody [NBP1-00790] - Analysis of EDG-3 (L41) pAb at 1:500 dilutionLane1:MCF-7 cell lysateLane2:Mouse spleen tissue lysateLane3:Rat spleen tissue lysate
Western Blot: S1P3/EDG-3 Antibody [NBP1-00790] - Analysis of EDG3 (L41) antibody in extracts from Jurkat cells.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-00790
    • Availability
      Product Discontinued

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S1P3/EDG-3 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 10-51 of Human EDG-3.
Specificity
EDG3 (L41) detects endogenous levels of EDG3 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
S1PR3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
Application Notes
Western blot (WB) analysis of EDG3 (L41) pAb in extracts from Jurkat cells.
Theoretical MW
42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for S1P3/EDG-3 Antibody

  • EDG3
  • EDG-3
  • EDG3FLJ37523
  • Endothelial differentiation G-protein coupled receptor 3
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 3
  • FLJ93220
  • G protein-coupled receptor, endothelial differentiation gene-3
  • LPB3
  • MGC71696
  • S1P receptor 3
  • S1P receptor EDG3
  • S1P receptor Edg-3
  • S1P3
  • S1PR3
  • sphingosine 1-phosphate receptor 3
  • Sphingosine 1-phosphate receptor Edg-3
  • sphingosine-1-phosphate receptor 3

Background

EDG3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG3 is expressed in heart, placenta, kidney, and liver tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol S1PR3
Entrez