S1P2/EDG-5/S1PR2 Antibody (368510) [Alexa Fluor® 750]

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Summary
Product Discontinued
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    • Catalog Number
      FAB3649S
    • Availability
      Product Discontinued

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S1P2/EDG-5/S1PR2 Antibody (368510) [Alexa Fluor® 750] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human S1P2/EDG-5
Met1-Val353
Accession # AAC98919
Specificity
Detects human S1P2/EDG-5. Stains human S1P2/EDG-5 transfectants but not irrelevant transfectants.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for S1P2/EDG-5/S1PR2 Antibody (368510) [Alexa Fluor® 750]

  • AGR16
  • EDG5
  • EDG-5
  • endothelial differentiation G-protein coupled receptor 5
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 5
  • GPCR13
  • GPCR18
  • H218
  • LPB2
  • S1P receptor 2
  • S1P receptor EDG5
  • S1P receptor Edg-5
  • S1P2
  • S1PR2
  • sphingosine 1-phosphate receptor 2
  • sphingosine 1-phosphate receptor Edg-5
  • sphingosine-1-phosphate receptor 2

Background

S1P2 (sphingosine 1-phosphate receptor-2), also known as EDG-5 (endothelial differentiation, G-protein coupled receptor-5), is a 353 amino acid (aa) seven-transmembrane receptor putative glycoprotein that binds the lysolipid phosphoric acid mediator, sphingosine 1-phosphate. Extracellular portions of human S1P2 show 82.5% aa identity with mouse S1P2 and 92% aa identity with human EDG-3, the most closely related family member. Both are expressed predominantly in the lung, heart, kidney, liver, spleen, thymus, testis and brain, mediating both mitogenic and anti-apoptotic effects.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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