RUNX2/CBFA1 Antibody (4B4)

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Western Blot: RUNX2/CBFA1 Antibody (4B4) [H00000860-M24] - Analysis of RUNX2 expression in LNCaP (Cat # L004V1).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00000860-M24
    • Availability
      Product Discontinued

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RUNX2/CBFA1 Antibody (4B4) Summary

Immunogen
RUNX2 (NP_001019801.1 311 a.a. - 450 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTS
Specificity
RUNX2 (4B4)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RUNX2
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RUNX2/CBFA1 Antibody (4B4)

  • Acute myeloid leukemia 3 protein
  • AML3CCD
  • CBFA1
  • CBFA1MGC120022
  • Core-binding factor subunit alpha-1
  • MGC120023
  • PEA2-alpha A
  • PEBP2A
  • PEBP2A1CCD1
  • PEBP2aA1
  • PEBP2-alpha A
  • runt domain, alpha subunit 1
  • runt-related transcription factor 2
  • RUNX2
  • SL3/AKV core-binding factor alpha A subunit
  • SL3-3 enhancer factor 1 alpha A subunit

Background

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for RUNX2/CBFA1 Antibody (H00000860-M24). (Showing 1 - 1 of 1 FAQ).

  1. We would like an anti-RUNX2 for IHC-P which share cross reactivity with Rat, but not with Human.
    • We don't have any data for our RUNX2 antibodies that confirms they will NOT detect the human protein. When we can confirm that an antibody will not react with a certain species, we display a (-) sign on the datasheet. Otherwise, if the species is not listed it means that it has not been tested.

Secondary Antibodies

 

Isotype Controls

Additional RUNX2/CBFA1 Products

Bioinformatics Tool for RUNX2/CBFA1 Antibody (H00000860-M24)

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Diseases for RUNX2/CBFA1 Antibody (H00000860-M24)

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Pathways for RUNX2/CBFA1 Antibody (H00000860-M24)

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PTMs for RUNX2/CBFA1 Antibody (H00000860-M24)

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Bioinformatics

Gene Symbol RUNX2
Entrez
OMIM
Uniprot