RSK1 Antibody

Images

 
Western Blot: RSK1 Antibody [NBP1-78029] - Western-blot analysis of p90 RSK1 imunoprecipitated from the mouse brain extract (B) and using RSK1-HRP as a probe. Immunoprecipitated negative control (A).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-78029
    • Availability
      Product Discontinued

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RSK1 Antibody Summary

Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-terminal region of human RSK1 protein.
Specificity
This antibody is directed against the human RSK1 protein. A BLAST analysis was used to suggest cross reactivity with RSK1 proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RPS6KA1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:200-1:1000
  • ELISA 1:2000-1:5000
Application Notes
This affinity purified antibody has been tested for use in ELISA, western blot, and immunoprecipitation. Expect a predominant band approximately 88 kDa in size corresponding - RSK1 by western blotting in the appropriate cell lysate or extract.

Reactivity Notes

Cross reactivity with RSK1 (and partial reactivity against RSK2 and RSK3) from other sources may occur but has not been tested.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.1 M Tris Chloride, 0.5 M Sodium Chloride, pH 8.0, 50% (v/v) Glycerol
Preservative
0.01% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for RSK1 Antibody

  • 90kD, polypeptide 1)
  • EC 2.7.11
  • EC 2.7.11.1,90 kDa ribosomal protein S6 kinase 1
  • HU-1
  • MAP kinase-activated protein kinase 1a
  • MAPK-activated protein kinase 1a
  • MAPKAP kinase 1a
  • MAPKAPK-1a
  • MAPKAPL1A
  • p90RSK1
  • p90S6K
  • ribosomal protein S6 kinase alpha 1
  • ribosomal protein S6 kinase alpha-1
  • ribosomal protein S6 kinase, 90kD, polypeptide 1
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1
  • Ribosomal S6 kinase 1
  • RPS6KA1
  • RSK
  • RSK1
  • RSK-1
  • RSK1p90-RSK 1
  • S6K-alpha 1
  • S6K-alpha-1

Background

RSK1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsk's appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RPS6KA1
Entrez