RRM1 Antibody

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Immunohistochemistry-Paraffin: RRM1 Antibody [NBP1-36439] Human Placenta

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

RRM1 Antibody Summary

Immunogen
A synthetic peptide from the C-terminus of human RRM1
Localization
Cytoplasm, Membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RRM1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.4) and 1.0% BSA
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for RRM1 Antibody

  • EC 1.17.4.1
  • R1
  • ribonucleoside-diphosphate reductase large subunit
  • Ribonucleoside-diphosphate reductase subunit M1
  • Ribonucleotide reductase large subunit
  • ribonucleotide reductase M1 polypeptide
  • ribonucleotide reductase M1
  • ribonucleotide reductase, large subunit
  • ribonucleotide reductase, R1 subunit
  • RIR1
  • RR1

Background

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RRM1
Entrez
Uniprot