ROR gamma/RORC/NR1F3 Antibody (B2D)

Images

 
Western Blot: ROR gamma/RORC/NR1F3 Antibody (B2D) [NBP2-00383] - Left: Mouse thymus (left) and spleen (right) nuclear cell lysates were loaded at 1x10e5 cells/lane, probed with 2 ug/mL of Anti-Mouse ROR gamma (t) ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
B2D
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

ROR gamma/RORC/NR1F3 Antibody (B2D) Summary

Immunogen
The immunogen for this antibody is RORg(t) (ROR gamma, Retinoid-Related Orphan Receptor gamma).
Specificity
The ROR-gamma(t) isoform differs from ROR-gamma by three unique amino acids at the amino terminus. Therefore, the B2D antibody will react with both the ROR-gamma and ROR-gamma(t) isoforms.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Rat
Gene
RORC
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This B2D antibody has been tested by western blot analysis of mouse thymus nuclear lysates. This B2D antibody can be used at a starting concentration of 2 ug/ml, however the optimal concentration should be determined for individual experimental conditions.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for ROR gamma/RORC/NR1F3 Antibody (B2D)

  • MGC129539
  • NR1F3
  • Nuclear receptor ROR gamma
  • Nuclear receptor ROR-gamma
  • Nuclear receptor RZR gamma
  • Nuclear receptor RZR-gamma
  • Nuclear receptor subfamily 1 group F member 3
  • RAR-Related Orphan Nuclear Receptor Variant 2
  • RAR-related orphan receptor C
  • RAR-related orphan receptor gamma
  • retinoic acid-binding receptor gamma
  • retinoid-related orphan receptor gamma
  • Retinoid-related orphan receptor-gamma
  • ROR gamma
  • RORC
  • RORG
  • RORGMGC129539
  • RZRG
  • RZRGRZR-GAMMA
  • TOR

Background

The B2D monoclonal antibody reacts with the mouse ROR-gamma(t) protein. ROR? is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes ROR-alpha and ROR-beta. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. ROR-gamma is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, ROR-gamma t, which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ "double-positive"thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

FAQs for ROR gamma/RORC/NR1F3 Antibody (NBP2-00383). (Showing 1 - 2 of 2 FAQ).

  1. Does ROR gamma/RORC/NR1F3 antibodies comes in lyophilized form?
    • Yes, we have 3 RORC antibodies delivere in lyophilized form: MAB61091, MAB61092, MAB6109.
  2. What the theoretical molecular weight for ROR gamma/RORC/NR1F3 antibodies?
    • The TMW of ROR gamma/RORC/NR1F3 antibodies is approximately 56 - 60.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol RORC