ROR beta Antibody

Images

 
Immunohistochemistry-Paraffin: ROR beta Antibody [NLS2564] - Anti-RORB / ROR Beta antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more
Immunohistochemistry-Paraffin: ROR beta Antibody [NLS2564] - Analysis of anti-ROR Beta antibody with human brain, thalamus.
Immunohistochemistry-Paraffin: ROR beta Antibody [NLS2564] - Anti-RORB / ROR Beta antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more

Product Details

Summary
Reactivity Hu, Bt, Bv, Ca, Eq, Mk, Op, Pm, Rb, ShSpecies Glossary
Applications ELISA, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

ROR beta Antibody Summary

Immunogen
Synthetic 15 amino acid peptide from hinge domain of human ROR Beta.
Epitope
hinge domain of human
Specificity
Human ROR Beta. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (93%), Canine (93%), Equine (93%), Sheep (93%), Opossum (93%), Bat (93%), Bovine (93%), Monkey (93%), Rabbit (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RORB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry-Paraffin 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (93%), Gibbon (93%), Marmoset (93%), Panda (93%), Platypus (93%), Rat (87%), Hamster (875), Elephant (87%), Mouse (80%), Porcine (80%), Chicken (80%), Lizard (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ROR beta Antibody

  • NR1F2
  • NR1F2nuclear receptor ROR-beta
  • Nuclear receptor RZR-beta
  • Nuclear receptor subfamily 1 group F member 2
  • RAR-related orphan receptor B
  • RAR-related orphan receptor beta
  • retinoic acid-binding receptor beta
  • retinoid-related orphan receptor beta
  • Retinoid-related orphan receptor-beta
  • ROR beta
  • RORB
  • ROR-BETA
  • RZRB
  • RZRBbA133M9.1
  • RZR-BETA

Background

Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing. Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility. ROR beta binds to the monomeric response elements containing the sequence AnnTAGGTCA as a monomer. An alternatively spliced isoform, ROR beta2, has been isolated from rats, and the expression of ROR beta2 is confined to the pineal gland and retina. ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but is characterized by a different amino-terminal domain. ROR beta expression has been documented in various regions of the mouse brain. ESTs have been isolated from human tissue libraries, including cancerous human kidney and normal brain, pineal and eye.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RORB
Entrez