RNF34 Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

RNF34 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-RNF34 full-length
Gene
RNF34

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for RNF34

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-RNF34 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RNF34 Overexpression Lysate (Denatured)

  • CARP1
  • Caspase regulator CARP1
  • Caspases-8 and -10-associated RING finger protein 1
  • E3 ubiquitin-protein ligase RNF34
  • EC 6.3.2
  • EC 6.3.2.-
  • FLJ21786
  • FYVE-RING finger protein Momo
  • hRFI
  • Human RING finger homologous to inhibitor of apoptosis protein
  • RFI
  • RIF
  • RIFF
  • ring finger protein 34CARP-1
  • RING finger protein RIFF

Background

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]. Transcript Variant: This variant (2) lacks an exon compared to variant 1. The resulting isoform (2) lacks one amino acid in the N-terminus, as compared isoform 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol RNF34