RhoB Antibody

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Product Details

Summary
Product Discontinued
View other related RhoB Primary Antibodies

Order Details


    • Catalog Number
      NBP1-03453
    • Availability
      Product Discontinued

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RhoB Antibody Summary

Immunogen
A synthetic peptide as a part of human, rat, mouse Rho-related GTP-binding protein RhoB (ARH6, ARHB, H6) conjugated to an immunogenic carrier protein was used as the immunogen.
Localization
subcellular location: late endosome membrane; lipid-anchor. cell membrane; lipid-anchor. nucleus. note: late endosomal membrane (geranylgeranylated form). plasma membrane (farnesylated form). also detected at the nuclear margin and in the nucleus.
Specificity
RhOB.
Clonality
Polyclonal
Host
Sheep
Gene
RHOB
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Positive Control
RhoB Lysate (NBL1-15350)

Reactivity Notes

Reacts with Human, Rat and Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for RhoB Antibody

  • ARH6MSTP081
  • ARHBAplysia RAS-related homolog 6
  • h6
  • MST081
  • oncogene RHO H6
  • ras homolog gene family, member B
  • Rho cDNA clone 6
  • RHOH6RhoB
  • rho-related GTP-binding protein RhoB

Background

Mediates apoptosis in neoplastically transformed cells after dna damage. not essential for development but affects cell adhesion and growth factor signaling in transformed cells. plays a negative role in tumorigenesis as deletion causes tumor formation. involved in intracellular protein trafficking of a number of proteins. targets pkn1 to endosomes and is involved in trafficking of the egf receptor from late endosomes to lysosomes. also required for stability and nuclear trafficking of akt1/akt which promotes endothelial cell survival during vascular development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for RhoB Antibody (NBP1-03453). (Showing 1 - 1 of 1 FAQ).

  1. What is the specificity of this antibody against RHOB as compared to RHOA or RHOC?
    • Our RhoB antibody, NBP1-03453, is specific for RhoB and no crossreactivity with RhoA or RhoC has been reported.

Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Diseases for RhoB Antibody (NBP1-03453)

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Bioinformatics

Gene Symbol RHOB
Entrez
Uniprot