RGS19 Antibody

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Product Details

Summary
Product Discontinued
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    • Catalog Number
      NB110-74846
    • Availability
      Product Discontinued

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RGS19 Antibody Summary

Immunogen
A synthetic peptide as a part of human, rat, mouse Regulator of G-protein signaling 19 (RGS19, G-alpha-interacting protein, GAIP, GNAI3IP,RGSGAIP) conjugated to an immunogenic carrier protein has been used as the immunogen.
Clonality
Polyclonal
Host
Rabbit
Gene
RGS19
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:2000
  • Immunohistochemistry 1:10-1:500
Control
RGS19 Overexpression Lysate

Reactivity Notes

Human, Rat and Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute with 0.15 ml sterilized water.

Alternate Names for RGS19 Antibody

  • G alpha interacting protein
  • GAIPG protein signalling regulator 19
  • G-alpha-interacting protein
  • GNAI3IP
  • guanine nucleotide binding protein alpha inhibiting activity polypeptide 3interacting protein
  • regulator of G-protein signaling 19
  • regulator of G-protein signalling 19
  • RGSGAIP

Background

G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.; FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. SUBCELLULAR LOCATION: Membrane; Lipid-anchor. TISSUE SPECIFICITY: Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol RGS19
Entrez
Uniprot