RFXANK Antibody (2B6)

Images

 
Western Blot: RFXANK Antibody (2B6) [NBP2-01758] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RFXANK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates ...read more
Immunocytochemistry/ Immunofluorescence: RFXANK Antibody (2B6) [NBP2-01758] Staining of COS7 cells transiently transfected by pCMV6-ENTRY RFXANK.
Immunohistochemistry-Paraffin: RFXANK Antibody (2B6) [NBP2-01758] - Staining of paraffin-embedded Human tonsil using anti-RFXANK mouse monoclonal antibody.
Immunohistochemistry-Paraffin: RFXANK Antibody (2B6) [NBP2-01758] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-RFXANK mouse monoclonal antibody.
Immunohistochemistry-Paraffin: RFXANK Antibody (2B6) [NBP2-01758] - Staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-RFXANK mouse monoclonal antibody.
Immunohistochemistry-Paraffin: RFXANK Antibody (2B6) [NBP2-01758] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-RFXANK mouse monoclonal antibody.
Immunohistochemistry-Paraffin: RFXANK Antibody (2B6) [NBP2-01758] - Staining of paraffin-embedded Human Kidney tissue using anti-RFXANK mouse monoclonal antibody.
Immunohistochemistry-Paraffin: RFXANK Antibody (2B6) [NBP2-01758] - Staining of paraffin-embedded Human lymphoma tissue using anti-RFXANK mouse monoclonal antibody.
Immunohistochemistry-Paraffin: RFXANK Antibody (2B6) [NBP2-01758] - Staining of paraffin-embedded Human pancreas tissue using anti-RFXANK mouse monoclonal antibody.

Product Details

Summary
Product Discontinued
View other related RFXANK Primary Antibodies

Order Details


    • Catalog Number
      NBP2-01758
    • Availability
      Product Discontinued

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RFXANK Antibody (2B6) Summary

Immunogen
Full length human recombinant protein of human RFXANK(NP_604389) produced in HEK293T cell.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
RFXANK
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for RFXANK Antibody (2B6)

  • ANKRA1Regulatory factor X subunit B
  • ankyrin repeat-containing regulatory factor X-associated protein
  • BLS
  • DNA-binding protein RFXANK
  • F14150_1
  • MGC138628
  • regulatory factor X-associated ankyrin-containing proteinAnkyrin repeat family A protein 1
  • RFXB
  • RFX-BRFX-Bdelta4

Background

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RFXANK
Entrez