Western Blot: RFX1 Antibody [NBP1-52652] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-RFX1 antibody used for WB at 0.04 mcg/ml (A) and ...read more
Human. Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Crab-eating macaque, Small-eared galago and Northern white-cheeked gibbon.
Alternate Names for RFX1 Antibody
Enhancer factor C
MHC class II regulatory factor RFX
MHC class II regulatory factor RFX1
Regulatory factor X 1
regulatory factor X, 1 (influences HLA class II expression)
trans-acting regulatory factor 1
Transcription factor RFX1
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.