Reticulum Cells Antibody (ED10)



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Reticulum Cells Antibody (ED10) Summary

Rat spleen cell homogenate
NB100-64648 recognizes reticular elements in the T cell areas of spleen, lymph nodes, Peyers patches, bronchus and gut associated lymphoid tissues (BALT and GALT). In the thymus a reticular pattern is observed in capsule and medulla (perivascular). Non-lymphoid organs: in liver, lung and small intestine, some ED10 positive reticular are found. No reaction is observed in skin, kidney, brain, pancreas and heart.
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  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:400-1:1000

Reactivity Notes

Reacts with Rat.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.09% Sodium Azide


Dendritic cells (DCs) are known as the professional antigen presenting cells. DCs perform the important role of capturing and processing antigen and presenting it to native T-helper cells to initiate the immune response. Distinct subsets of DCs have been described, they include interdigitating reticulum cells. The antigen recognized by NB100-64648 is found on a subpopulation (approximately 5%) of circulating monocytes and peritoneal macrophages, as well as on in vitro LPS and IFN stimulated macrophages and on all macrophages after 3 weeks in culture. It is absent from all other blood cells. Detects a subpopulation of reticulum cells in T-cell areas of lymph nodes and spleen and their in vitro correlates. It is also useful for the detection of a macrophage subpopulation in the thymus. A minor but distinct population of leukocytes in the kidney cortex is also positively stained by ab15683. The antigen is absent in the skin.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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