Renal Cell Carcinoma (gp200) Antibody (S19-P)

Images

 
Immunohistochemistry-Paraffin: Renal Cell Carcinoma (gp200) Antibody (S19-P) [NBP1-30146] - human renal cell carcinoma stained with NBP1-30146 shows strong positive immunostaining of tumor cells.

Order Details


    • Catalog Number
      NBP1-30146
    • Availability
      Product Discontinued

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Renal Cell Carcinoma (gp200) Antibody (S19-P) Summary

Immunogen
Peptide derived from N-terminal sequence of human CD205.
Specificity
This antibody is specific for the N terminus of CD205
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
LY75
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:100
  • Immunohistochemistry-Paraffin 1:100-200
Application Notes
For use in Immunohistochemistry frozen and paraffin embedded sections. For 0.1ml, 0.5ml and 1.0ml sizes, use recommended dilutions. For 7.0ml and 15.0ml sizes, products should be used undiluted.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
20mM Tris/HCl (pH 8.0) and 20 mg/ml BSA
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

The 7mL and 15 mL sizes that this product is available in is a pre-diluted size and no additional dilutions are required before using this item for the intended application.

Alternate Names for Renal Cell Carcinoma (gp200) Antibody (S19-P)

  • CD205LY-75
  • CLEC13BLy-75
  • C-type lectin domain family 13 member B
  • DEC-205CD205 antigen
  • GP200-MR6
  • lymphocyte antigen 75

Background

gp200 is a surface membrane glycoprotein expressed on human embryonal carcinoma and is a malignant stem cell of testicular tumors. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Of other normal tissues examined, the gp200 is also localized along the luminal surfaces of breast lobules and ducts, the luminal surface of the epididymal tubular epithelium, within the cytoplasm of parathyroid parenchymal cells, and focally within the colloid of thyroid follicles. Thirty one other normal tissues do not express similar or cross reacting antigens. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LY75
Entrez
Uniprot