RELM beta Antibody

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Western Blot: RELM beta Antibody [NB200-205] - Analysis of transfected 293T cells. 1:500 dilution.

Product Details

Summary
Product Discontinued
View other related RELM beta Primary Antibodies

Order Details


    • Catalog Number
      NB200-205
    • Availability
      Product Discontinued

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RELM beta Antibody Summary

Immunogen
Reacts with the residues 31-44 of the mouse RELM alpha protein.
Specificity
Reacts with the residues 31-44 of the mouse RELMalpha protein.
Clonality
Polyclonal
Host
Rabbit
Gene
RETNLB
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500 -1:1000
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This antibody has only been tested in Western blot. Bands appear at about 10-12 kDa. mRELM-alpha should migrate as a monomer under complete reducing conditions. Larger bands may appear if run under non-reducing conditions. Use at 1:500 to 1:1,000 dilution. *The investigator should determine the optimal dilution for this specific application.

Reactivity Notes

Mouse

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for RELM beta Antibody

  • C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 2
  • CCRG
  • Colon and small intestine-specific cysteine-rich protein
  • Colon carcinoma-related gene protein
  • cysteine-rich secreted A12-alpha-like protein 1
  • Cysteine-rich secreted protein A12-alpha-like 1
  • Cysteine-rich secreted protein FIZZ2
  • FIZZ1
  • FIZZ2RELM-beta
  • found in inflammatory zone 1
  • HXCP2XCP2
  • RELM beta
  • RELMb
  • RELMbeta
  • resistin like beta
  • resistin-like beta
  • RETNL2

Background

A family of resistin-like molecules (RELMs) has been identified in rodents and humans. Resistin is a hormone produced by fat cells. RELMalpha is a secreted protein that has a restricted tissue distribution with highest levels in adipose tissue. Another family member, RELMbeta, is a secreted protein expressed only in the gastrointestinal tract, particularly the colon, in both mouse and human. RELMbeta gene expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation. Resistin and the RELMs share a cysteine composition and other signature features. Thus, the RELMs together with resistin comprise a class of tissue-specific signaling molecules. mRELM-alpha should migrate as a monomer under complete reducing conditions. However, it migrates as dimers, trimers, and even higher order multimers under non-reducing conditions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RETNLB
Entrez