RelB Antibody


Western Blot: Rel B Antibody [NBP1-62001] - Analysis of extracts from HeLa cells, using Rel B Antibody. The lane on the right is treated with the synthesized peptide.

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RelB Antibody Summary

The antiserum was produced against synthesized peptide derived from human RelB. The immunogen region is: C-terminal.
RelB (Ab-552) Antibody detects endogenous levels of total RelB protein.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • ELISA 1:20000

Reactivity Notes


Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
0.02% Sodium Azide
1 mg/ml
Immunogen affinity purified

Alternate Names for RelB Antibody

  • IREL
  • I-Rel
  • nuclear factor of kappalight polypeptide gene enhancer in B-cells 3
  • RelB
  • v-rel reticuloendotheliosis viral oncogene homolog B


RelB, also known as I-Rel, is a member of the Rel transcription factor family which also include; RelA-p65, c-Rel, NF-kB1 p100/52 and NF-kB2 p105/50 (1). Unlike other Rel-related protein, RelB does not bind to DNA or to inhibitor IkB, but is instead sequestered in the cytoplasm by precursor p100. Once p100 is processed, the p52/RelB complex translocates into the nucleus (2). RelB is also the transcription factor that has been associated most directly with dendritic cells (DCs) differentiation and function (3). It is upregulated and translocated into the nuclei of DC in response to various stimuli. RelB is also essential for generating a specific DC subset (CD11c+/CD11b+/CD8-/Dec205-) from hematopoietic stem cells (5).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Blogs on RelB.

NFkB and p62 Both Activate and Regulate Inflammation
Nuclear factor kappa-light-chain-enhancer of activated B cells (NFkB) is a protein complex that regulates DNA transcription and is a critical regulator of cell survival. NFkB has long been known as a primer of inflammation, however researchers are...  Read full blog post.

RelA/NF-kB - A proinflammatory signaling pathway with roles in immunity and cancer
The inflammatory response consists of a complex network of signaling pathways that regulate a diverse set of cytokines, growth factors, adhesion molecules, and transcription factors (1). Of the proinflammatory signaling pathways the NF-kB family is...  Read full blog post.

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Gene Symbol RELB