Biological Strategies: Western Blot: RCOR1/CoREST Antibody [NB600-240] - Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit ...read more
Immunohistochemistry-Paraffin: RCOR1/CoREST Antibody [NB600-240] - Human skin carcinoma. Antibody: Affinity purified rabbit anti-CoREST used at a dilution of 1:5,000 (0.2ug/ml). Detection: DAB
A synthetic peptide that maps to a region between residues 425 and the C-terminus (residue 482) of human REST (RE1-silencing transcription factor) corepressor using the numbering given in entry NP_055971.1 (GeneID 23186)
Immunogen affinity purified
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Brain type II sodium channels are important in neuronal phenotyping and are only seen at high levels in neurons. Studies have shown that CoREST functions as a corepressor for REST. This interaction between REST and CoREST is accomplished by means of a single zinc finger binding motif originating from REST. Together, the REST-CoREST complex mediates long term repression of the type II sodium channel gene (1).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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