RCC2 Antibody

Images

 
Immunohistochemistry-Paraffin: RCC2 Antibody [NBP1-68628] - Analysis of paraffin-embedded human breast carcinoma tissue, using RCC2 Antibody. The picture on the right is treated with the synthesized peptide.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-68628
    • Availability
      Product Discontinued

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RCC2 Antibody Summary

Immunogen
The antiserum was produced against synthesized peptide derived from human RCC2. The immunogen region is: C-terminal.
Specificity
RCC2 Antibody detects endogenous levels of total RCC2 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
RCC2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA 1:5000
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100

Reactivity Notes

Human,Mouse

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for RCC2 Antibody

  • DKFZp762N0610
  • KIAA1470
  • protein RCC2
  • RCC1-like protein TD-60
  • regulator of chromosome condensation 2
  • TD60
  • TD-60
  • Telophase disk protein of 60 kDa

Background

RCC2 (regulator of chromosome condensation 2) is a member of the RCC1 family of guanine nucleotide exchange factors. RCC2 has been identified as part of the chromosomal passenger complex (CPC) which coordinates the chromosomal and cytoskeletal events of mitosis. Chromosomal passengers are proteins present in complexes with aurora B, inner centromeric protein (INCENP), survivin, and borealin. RCC2 has been demonstrated to be required for the recruitment of survivin and aurora B and is essential for proper chromosome segregation and the completion of cell cleavage. Loss of RCC2 inhibits spindle assembly, activates the spindle assembly checkpoint, and blocks cells in prometaphase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Array NBP1-68628

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Bioinformatics

Gene Symbol RCC2
Uniprot