48 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NBP1-40622 in the following applications:
Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Alternate Names for RBBP4/RbAp48 Antibody (EPR3411)
CAF-1 subunit C
Chromatin assembly factor 1 subunit C
Chromatin assembly factor I p48 subunit
chromatin assembly factor/CAF-1 p48 subunit
histone-binding protein RBBP4
MSI1 protein homolog
Nucleosome-remodeling factor subunit RBAP48
retinoblastoma binding protein 4
Retinoblastoma-binding protein 4CAF-I 48 kDa subunit
Retinoblastoma-binding protein p48
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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