RbAp46 Antibody [Biotin]

Images

 
There are currently no images for RbAp46 Antibody (NB100-74521).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, FiSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin
Concentration
1.0 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price

RbAp46 Antibody [Biotin] Summary

Immunogen
Synthetic peptide corresponding to residues M(1) A S K E M F E D T V E E(13) C of human RbAp46.
Localization
Nuclear.
Specificity
NB120-3535 detects retinoblastoma protein (Rb) associated protein 46 (RbAp46) from human cells.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RBBP7
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
Application Notes
This antibody is useful for Western Blot. By Western blot, this antibody detects an ~46 kDa protein representing RbAp46 Biotin from HeLa cell lysate
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Reactivity Notes

Expected cross-reactivity with Rat (100%), Xenopus Laevis (92%), and Chicken (84%) base on sequence homology. Mouse reactivity reported in scientific literature (PMID: 14645126).

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
No Buffer
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for RbAp46 Antibody [Biotin]

  • G1/S transition control protein-binding protein RbAp46
  • Histone acetyltransferase type B subunit 2
  • histone-binding protein RBBP7
  • MGC138867
  • Nucleosome-remodeling factor subunit RBAP46
  • RbAp46
  • RBBP-7
  • retinoblastoma binding protein 7
  • Retinoblastoma-binding protein 7MGC138868
  • Retinoblastoma-binding protein p46
  • retinoblastoma-binding protein RbAp46

Background

Retinoblastoma protein (Rb) associated protein 46 (RbAp46) is a nuclear protein that has been shown to interact directly with retinoblastoma protein and is a component of the mSin3 corepressor complex as are the histone deacetylase proteins (HDACs). RbAp46 shares about 75% sequence identity with the closely related RbAp48, and appears to be functionally related to the yeast MSI1 protein in that overexpression of RbAp46 suppresses heat shock sensitivity in a RAS pathway dependent manner. RbAp46 has also been demonstrated to be up-regulated by the Wilms' tumor suppressor gene product, WT1. Additionally, cells transfected with RbAp46 have shown strong inhibition of growth.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-41201
Species: Hu
Applications: WB, ChIP, ICC/IF, IHC, IP
NB100-56598
Species: Hu, Mu
Applications: WB, IHC, IHC-Fr, IHC-P
NB100-56340
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-Fr, IHC-P
NBP1-87109
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB110-60011
Species: Hu, Mu
Applications: WB, Simple Western, IHC, IHC-Fr, IHC-P, IP
NB500-171
Species: Hu, Mu, Rt, Xp, Ye
Applications: WB, ChIP, ICC/IF, IHC, IHC-P
NB21-2024
Species: Hu, Mu, Rt, Ma
Applications: WB, ChIP, DB, ICC/IF
NB120-11012
Species: Hu, Bv(-), Ca(-), Eq(-), Gp(-), Mu(-), Po(-)
Applications: WB, ELISA, ICC/IF, IP
NBL1-11569
Species: Hu
NB100-360
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP2-07996
Species: Hu
H00008360-R01
Species: Hu
NBL1-11570
Species: Hu
NBP2-10888
Species: Hu
H00008365-M01
Species: Hu
Applications: ELISA, ICC/IF
NBL1-11567
Species: Hu
NBP2-52486
Species: Hu
Applications: WB, ELISA, Flow, IHC, IHC-P, CyTOF-ready, ICC, IF
NBP1-88356
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-03993
Species: Hu, Bv, Ca, Pm
Applications: WB, IHC, IHC-P
NB100-74521
Species: Hu, Mu, Fi
Applications: WB

Publications for RbAp46 Antibody (NB100-74521) (0)

There are no publications for RbAp46 Antibody (NB100-74521).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for RbAp46 Antibody (NB100-74521) (0)

There are no reviews for RbAp46 Antibody (NB100-74521). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for RbAp46 Antibody (NB100-74521) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional RbAp46 Products

Bioinformatics Tool for RbAp46 Antibody (NB100-74521)

Discover related pathways, diseases and genes to RbAp46 Antibody (NB100-74521). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for RbAp46 Antibody (NB100-74521)

Discover more about diseases related to RbAp46 Antibody (NB100-74521).
 

Pathways for RbAp46 Antibody (NB100-74521)

View related products by pathway.

PTMs for RbAp46 Antibody (NB100-74521)

Learn more about PTMs related to RbAp46 Antibody (NB100-74521).
 

Research Areas for RbAp46 Antibody (NB100-74521)

Find related products by research area.

Blogs on RbAp46

There are no specific blogs for RbAp46, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our RbAp46 Antibody [Biotin] and receive a gift card or discount.

Bioinformatics

Gene Symbol RBBP7