RARRES3 Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-93436
    • Availability
      Product Discontinued

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RARRES3 Antibody Summary

Immunogen
Peptide with sequence KSRCKQVEKAKVE corresponding to internal region according to NP_004576.2.
Epitope
KSRCKQVEKAKVE
Clonality
Polyclonal
Host
Goat
Gene
RARRES3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:128000
Application Notes
WB: Preliminary experiments gave bands at approx. 22 kDa band and 55 kDa band in human thymus lysates after 1 ug/ml antibody staining. The 55 kDa band was observed in all tissues tested. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 18.8 kDa band according to NP_004576.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
Publications
Read Publication using NB100-93436.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for RARRES3 Antibody

  • HRASLS4
  • PLA1/2-3
  • RARRES3
  • RAR-responsive protein TIG3
  • retinoic acid receptor responder (tazarotene induced) 3
  • retinoic acid receptor responder protein 3
  • retinoic acid-inducible gene 1
  • Retinoid-inducible gene 1 protein
  • RIG1
  • Tazarotene-induced gene 3 protein
  • TIG3
  • TIG3MGC8906

Background

Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for RARRES3 Antibody (NB100-93436)(1)


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RARRES3
Entrez
Uniprot