RAGE Antibody


Western Blot: RAGE Antibody [NBP1-19732] Extracts from HEK293A cells.
Immunohistochemistry-Paraffin: RAGE Antibody [NBP1-19732] - Human lung carcinoma tissue.
Western Blot: RAGE Antibody [NBP1-19732] - extracts from LOVO cells.

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RAGE Antibody Summary

Synthetic peptide, corresponding to amino acids 150-205 of Human AGER / RAGE.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of RAGE (E182) pAb in extracts from HEK293A cells.
Immunohistochemistry (IHC) analyzes of RAGE (E182) pAb in paraffin-embedded human lung carcinoma tissue.
Theoretical MW
43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
RAGE Lysate (NBP2-66287)

Reactivity Notes

Cross reacts with Human.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
15mM Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for RAGE Antibody

  • AGER
  • EC
  • MOK Protein Kinase
  • MOK
  • RAGE
  • RAGE-1
  • Renal tumor antigen 1
  • renal tumor antigen


Advanced glycosylation end products of proteins (AGEs) are nonenzymatically glycosylated proteins that are associated with a variety of conditions including diabetes and other vascular disorders, as well as amyloidosis. These proteins regulate cellular functions via specific cell surface acceptor molecules, such as RAGE (receptor for advanced glycosylation end products). RAGE is a type 1 membrane protein that is found on the surface of endothelial cells, mononuclear phagocytes and vascular smooth muscle cells. Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkappaB. Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 Ras and MAP kinase, which leads to activation of transcription.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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S100A12 (Calgranulin C) belongs to the S100 family of calcium-binding proteins. The 20 members of this group share EF-hand domains which are involved in binding of calcium. S100A12 is expressed by granulocytes, whereas its expression by monocytes rema...  Read full blog post.

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Gene Symbol MOK