Raf-1 RNAi

Images

 
Western Blot: Raf-1 RNAi [H00005894-R01V] - Analysis of RAF1 over-expressed 293 cell line, cotransfected with RAF1 Validated Chimera RNAi or non-transfected control. Blot probed with H00005894-M03. GAPDH (36.1 kDa) used ...read more
RNAi sequence position: Raf-1 RNAi [H00005894-R01V]

Product Details

Summary
Product Discontinued
View other related Raf-1 RNAi

Order Details


    • Catalog Number
      H00005894-R01V
    • Availability
      Product Discontinued

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Raf-1 RNAi Summary

Specificity
Homo sapiens v-raf-1 murine leukemia viral oncogene homolog 1, mRNA
Gene
RAF1

Applications/Dilutions

Application Notes
This RNAi causes effective protein knockdown which has been antibody validated.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
DEPC-treated Water

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Raf-1 RNAi

  • cRaf
  • c-Raf
  • c-Raf-1
  • CRAFraf proto-oncogene serine/threonine protein kinase
  • EC 2.7.11
  • EC 2.7.11.1
  • NS5
  • Proto-oncogene c-RAF
  • RAF proto-oncogene serine/threonine-protein kinase
  • RAF
  • Raf1
  • Raf-1
  • Raf-1Oncogene RAF1
  • v-raf-1 murine leukemia viral oncogene homolog 1
  • v-Raf-1

Background

Position of the Chimera RNAi. The related RNAi products listed were designed from different accesion number but sharing the same RNAi sequence. Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Video Protocols

WB Video Protocol

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Diseases for Raf-1 RNAi (H00005894-R01V)

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Bioinformatics

Gene Symbol RAF1
Entrez