RAD18 Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

RAD18 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-RAD18 full-length
Gene
RAD18

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for RAD18

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-RAD18 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RAD18 Overexpression Lysate (Denatured)

  • EC 6.3.2.-
  • hHR18
  • hRAD18
  • postreplication repair protein hRAD18p
  • Postreplication repair protein RAD18
  • RAD18 homolog (S. cerevisiae)
  • RAD18, S. cerevisiae, homolog
  • RING finger protein 73
  • RNF73E3 ubiquitin-protein ligase RAD18

Background

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Publications for RAD18 Lysate (H00056852-T01) (0)

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Product General Protocols

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Video Protocols

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Bioinformatics

Gene Symbol RAD18